2024 年第 12 期 第 0 卷

心衰康神阙穴贴敷联合西医标准化治疗方案对慢性心力衰竭患者超声心动图结果及6分钟步行试验距离的影响

Effects of Xinshuaikang Shenque acupoint application combined with standardized treatment regimen of western medicine on the results of echocardiography and the distance of 6 min walk test in patients with chronic heart failure

作者：杨皎张晶贾磊

英文作者：Yang Jiao Zhang Jing Jia Lei

单位：内蒙古自治区中医医院心病科，呼和浩特010010

英文单位：Department of Cardiology Inner Mongolia Autonomous Region Traditional Chinese Medicine Hospital Hohhot 010010 China

关键词：慢性心力衰竭；心衰康；穴位贴敷；超声心动图；6min步行试验

英文关键词：Chronicheartfailure;Xinshuaikang;Acupointapplication;Echocardiography;6minwalktest

• 摘要：

• 目的 探究心衰康神阙穴贴敷联合西医标准化治疗方案对慢性心力衰竭（CHF）患者超声心动图结果及6 min步行试验(6MWT)距离的影响。方法 选取2022年6月至2023年6月内蒙古自治区中医医院收治的98例CHF患者为研究对象，随机数字表法分为联合组和标准治疗组，各49例。标准治疗组采用西医标准化药物治疗，联合组加用心衰康神阙穴贴敷进行治疗。比较2组临床疗效、中医证候积分、超声心动图指标［左心室射血分数（LVEF）、每搏输出量（SV）、左心室舒张末期内径（LVEDD）、左心室收缩末期内径（LVESD）］、血清学指标［N末端B型脑钠肽前体（NT-proBNP）、心肌肌钙蛋白Ⅰ（cTnI）、血管紧张素Ⅱ（AngⅡ）］、运动耐力及生活质量指标［6MWT距离、明尼苏达心力衰竭生活质量量表（MLHFQ）］及不良反应发生情况。结果 治疗后，联合组总有效率明显高于标准治疗组［71.4%（35/49）比51.0%（25/49）］（P=0.038）。治疗后，2组患者的倦怠乏力、喘息气短、肢体沉重、心悸盗汗评分均低于治疗前，且联合组明显低于标准治疗组（均P＜0.05）。治疗后，2组患者的LVEF、SV、6MWT距离均明显高于治疗前，且联合组明显高于标准治疗组，LVEDD、LVESD、NT-proBNP、cTnI、AngⅡ、MLHFQ均明显低于治疗前，且联合组明显低于标准治疗组（均P＜0.05）。2组患者不良反应发生率比较差异无统计学意义（P=0.505）。结论 心衰康神阙穴贴敷联合西医标准化治疗方案对CHF患者的临床疗效更好，可以有效改善患者心功能，增加运动耐力，提升患者生活质量。

• Objective To investigate the effects of Xinshuaikang Shenque acupoint application combined with standardized treatment regimen of western medicine on the results of echocardiography and the distance of 6 min walk test (6MWT) in patients with chronic heart failure (CHF). Methods A total of 98 patients with CHF admitted to Inner Mongolia Autonomous Region Traditional Chinese Medicine Hospital from June 2022 to June 2023 were selected as the research objects, and they were divided into combined group and standard treatment group by random number table method, with 49 cases in each group. The standard treatment group was treated with standardized western medicine, and the combined treatment group was treated with Xinshuankang Shenque acupoint application. The clinical efficacy, traditional Chinese medicine syndrome scores, echocardiographic indicators ［left ventricular ejection fraction (LVEF), stroke volume (SV), left ventricular end diastolic diameter (LVEDD), left ventricular end systolic diameter (LVESD)］, serological indicators ［N-terminal pro-B-type natriuretic peptide (NT-proBNP), cardiac troponin Ⅰ (cTnI), angiotensin Ⅱ (AngⅡ)］, exercise tolerance  and quality of life indicators ［6MWT distance, Minnesota Living with Heart Failure Questionnaire (MLHFQ)］, and adverse reactions were compared between the two groups. Results After treatment, the total effective rate of the combined group was significantly higher than that of the standard treatment group ［71.4%(35/49) vs 51.0%(25/49)］(P=0.038). After treatment, the scores of fatigue, shortness of breath, heavy limbs, palpitation and night sweat in the two groups were lower than those before treatment, and those in the combined group were significantly lower than those in the standard treatment group (all P＜0.05). After treatment, LVEF, SV and 6MWT distance in both groups were significantly higher than those before treatment, and those in the combined group were significantly higher than those in the standard treatment group. LVEDD, LVESD, NT-proBNP, cTnI, AngⅡ and MLHFQ were significantly lower than those before treatment, and those in the combined group were significantly lower than those in the standard treatment group (all P＜0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P=0.505). Conclusion Xinshuaikang Shenque acupoint application combined with standardized western medicine treatment has better clinical effect on CHF patients, which can effectively improve the cardiac function of patients, increase exercise endurance and improve the quality of life of patients.