2022 年第 11 期 第 17 卷

维生素D与1型糖尿病及其微血管并发症相关性的研究进展

Research progress on the relationship between vitamin D and type 1 diabetes mellitus and microvascular complications of diabetes

作者：任留留1陈爱荣2陆静1张丽娟1

英文作者：Ren Liuliu1 Chen Airong2 Lu Jing1 Zhang Lijuan1

单位：1兰州大学第二临床医学院，兰州730000；2兰州大学第二医院内分泌与代谢病科，兰州730000

英文单位：1The Second Clinical Medical School Lanzhou University Lanzhou 730000 China; 2Department of Endocrinology and Metabolic Diseases Lanzhou University Second Hospital Lanzhou 730000 China

关键词：1型糖尿病；维生素D；糖尿病微血管并发症

英文关键词：Type1diabetesmellitus;VitaminD;Microvascularcomplicationsofdiabetes

• 摘要：

• 1型糖尿病（T1DM）是好发于青少年的慢性疾病，其急性并发症以酮症酸中毒多见，慢性并发症以微血管并发症多见，对青少年的生活质量及远期预后具有重大影响。维生素D具有免疫调节特性，不仅参与T1DM发病过程，并可能在预防或减缓T1DM并发症发生发展的过程中发挥作用。为及时预防T1DM微血管并发症发生，本文就维生素D与T1DM及微血管并发症的相关性展开综述。

• Type 1 diabetes mellitus (T1DM) is a chronic disease frequently occurring in young people. Its acute complications are mostly ketoacidosis. Its chronic complications are mostly microvascular complications and have a significant impact on the quality of life and long-term prognosis of adolescents. Vitamin D is not only involved in the pathogenesis of T1DM, but also plays an important role in the occurrence and development of T1DM complications. In order to prevent microangiogenesis in T1DM in a timely manner, this article reviews the relationship between vitamin D and T1DM and its microvascular complications.