2022 年第 2 期 第 17 卷

无创冠状动脉功能检查的研究进展

Research progress of noninvasive coronary artery functional examination

作者：余俊王巍

英文作者：Yu Jun Wang Wei

单位：北京协和医学院国家心血管病中心中国医学科学院阜外医院结构性心脏病中心二病区，北京100037

英文单位：Second Ward of Structural Heart Disease Center Peking Union Medical College National Cardiovascular Center Fuwai Hospital Chinese Academy of Medical Sciences Beijing 100037 China

关键词：冠心病（冠状动脉粥样硬化性心脏病）；血流储备分数；冠状动脉造影；功能性检查

英文关键词：Coronaryatheroscleroticheartdisease;Fractionalflowreserve;Coronaryarteryangiography;Functionalexamination

• 摘要：

• 血流储备分数(FFR)指导冠状动脉血运重建具有更好的临床预后。由于FFR是有创操作，增加了患者的风险和费用，在外科领域的实际应用和推广中受到限制。无创冠状动脉功能检查技术包括定量FFR（QFR）和基于冠状动脉CT血管造影计算得出的FFR（FFR-CT）。本文对无创冠状动脉功能检查技术QFR和FFR-CT的临床安全性和有效性进行综述，以期指导冠状动脉血运重建。

• Fractional flow reserve (FFR) guiding coronary revascularization has a better clinical prognosis. However, as an invasive operation test, FFR increases the risk and the cost of patients. Therefore, the practical application of FFR in the field of surgery is limited. Noninvasive coronary artery functional examination technology mainly includes quantitative FFR (QFR) and FFR calculated based on coronary CT angiography (FFR-CT). This article reviews the clinical safety and effectiveness of QFR and FFR-CT, in order to guide coronary revascularization.