2021 年第 10 期 第 16 卷

子宫内膜癌筛查方法及其研究进展

Screening methods and research progress on endometrial cancer gment

作者：王云露樊学芬郭钰珍陈小芸郑荣芳

英文作者：Wang Yunlu Fan Xuefen Guo Yuzhen Chen Xiaoyun Zheng Rongfang

单位：兰州大学第二医院妇科730000

英文单位：Department of Gynecology Lanzhou University Second Hospital Lanzhou 730000 China

关键词：子宫内膜癌；基因检测；生物标志物；血液光谱；子宫内膜微生物群

英文关键词：Endometrialcancer;Genetictesting;Tumormarkers;Bloodspectroscopy;Endometrialmicrobiome 

• 摘要：

• 子宫内膜癌是常见的女性生殖道恶性肿瘤之一。近年来，受生活方式和环境等因素影响，子宫内膜癌的发病率逐渐上升。病理检查为目前诊断子宫内膜病变的金标准，由于取样技术的侵入性在临床筛查的推广中受限。利用微创采样技术、血液光谱检测技术、基因检测方法研究新型生物标志物和探索子宫内膜微生物群在筛查中的价值在临床中开展的越来越多。本文就子宫内膜癌的筛查方法及其研究进展进行综述。

• Endometrial cancer （EC） is one of the most common malignancies of the female genital tract. In recent years, the morbidity of EC gradually increases due to the lifestyle and environmental influences. Currently, pathological examination is the gold standard to diagnose endometrial diseases, but it cannot be widely used to screen because of invasive inspection. Thus, the value of new tumor markers and endometrial microbiome in screen EC is performed increasingly by minimally invasive approach, blood spectroscopy and genetic testing. This article reviews screening methods and research progress on EC.