2021 年第 4 期 第 16 卷

椎动脉狭窄和冠状动脉狭窄之间的相关性研究

The relationship between the vertebral artery stenosis and coronary artery stenosis

作者：王力锋1何晓芬1周子杰2

英文作者：Wang Lifeng1 He Xiaofen1 Zhou Zijie2

单位：1首都医科大学附属北京安贞医院神经介入科100029；2首都医科大学附属北京安贞医院药理基地100029

英文单位：1Department of Interventional Neuroradiology Beijing Anzhen Hospital Capital Medical University Beijing 100029 China; 2Pharmacological Research Beijing Anzhen Hospital Capital Medical University Beijing 100029 China

关键词：

英文关键词：Vertebralarterystenosis;Coronaryarterystenosis;Simultaneouslycerebral-coronaryangiography

• 摘要：

• 目的 探讨经同期椎动脉造影和冠状动脉造影证实的椎动脉狭窄与冠状动脉狭窄之间的相关性。方法 纳入2014年1月至2015年8月于首都医科大学附属北京安贞医院同时行椎动脉造影和冠状动脉造影的173例患者的临床资料。根据椎动脉狭窄的程度将患者分为椎动脉轻度狭窄组（狭窄＜50%，122例）和椎动脉重度狭窄组（狭窄≥50%，51例），分析椎动脉狭窄的危险因素。根据患者冠状动脉狭窄情况，将冠状动脉狭窄的患者分为冠状动脉轻度狭窄组（狭窄＜70%，58例）和冠状动脉重度狭窄组（狭窄≥70%，115例），分析冠状动脉狭窄的危险因素。对患者椎动脉和冠状动脉狭窄的具体情况进行统计分析，并探讨二者之间的相关性。结果 统计结果显示年龄、男性、高血压、冠心病（冠状动脉粥样硬化性心脏病）是椎动脉狭窄和冠状动脉狭窄的共同危险因素。椎动脉重度狭窄组总的冠状动脉重度狭窄患者比例以及左前降支、左回旋支、右冠状动脉重度狭窄患者比例明显高于椎动脉轻度狭窄组［80.4%（41/51）比60.7%（74/122）、66.7%（34/51）比42.6%（52/122）、47.1%（24/51）比28.7%（35/122）、54.9%（28/51）比32.8%（40/122）］，差异均有统计学意义（均P<0.05）。结论 椎动脉狭窄和冠状动脉狭窄的危险因素基本相同。椎动脉狭窄和冠状动脉狭窄之间存在统计学相关性，对椎动脉狭窄的筛选可以为冠状动脉评估提供依据。

• Objective To discuss the relationship between vertebral artery stenosis and coronary artery stenosis confirmed by the concurrent  vertebral angiography and coronary angiography. Methods The clinical data of 173 patients who underwent both vertebral angiography and coronary angiography in Beijing Anzhen Hospital, Capital Medical University from January 2014 to August 2015 were included. According to the degree of vertebral artery stenosis, the patients were divided into mild vertebral artery stenosis group (stenosis<50%, 122 cases) and severe vertebral artery stenosis group (stenosis≥50%, 51 cases), and the risk factors of vertebral artery stenosis were analyzed. According to the degree of coronary artery stenosis, patients with coronary artery stenosis were divided into mild coronary artery stenosis group (stenosis<70%, 58 cases) and severe coronary artery stenosis group (stenosis≥70%, 115 cases), and the risk factors of coronary artery stenosis were analyzed. The specific situation of patients with vertebral artery and coronary artery stenosis were statistically analyzed, and the correlation between them was explored. Results Statistical results showed that age, male, hypertension and coronary atherosclerotic heart disease were common risk factors of vertebral artery stenosis and coronary artery stenosis. The total proportion of patients with severe coronary artery stenosis and the proportions of patients with severe left anterior descending, left circumflex and right coronary artery stenosis in severe vertebral artery stenosis group were significantly higher than those in mild vertebral artery stenosis group ［80.4%（41/51） vs 60.7%（74/122）, 66.7%（34/51） vs 42.6%（52/122）, 47.1%（24/51） vs 28.7%（35/122）, 54.9%（28/51） vs 32.8%（40/122）］(all P<0.05). Conclusions  Risk factors of vertebral artery stenosis and the coronary are essentially the same. Vertebral artery stenosis is statistically associated with the coronary artery stenosis. Screening vertebral artery is useful for evaluating coronary artery stenosis.