2020 年第 7 期 第 15 卷

生活方式干预在中青年代谢综合征患者中的效果评估 

Effect evaluation of lifestyle intervention in young and middle-aged patients with metabolic syndrome

作者：张梦婷1臧晓鹭2吴丽娜3郑宇明2

英文作者：Zhang Mengting1 Zang Xiaolu2 Wu Lina3 Zheng Yuming2 e

单位：1华中科技大学同济医学院附属武汉中心医院宣传科430014；2华中科技大学同济医学院附属武汉中心医院体检中心430014；3华中科技大学同济医学院附属武汉中心医院医学资讯科430014

英文单位：1Publicity Division Wuhan Central Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology Wuhan 430014 China； 2Medical Examination Center Wuhan Central Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology Wuhan 430014 China； 3Department of Medical Information Wuhan Central Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology Wuhan 430014 China

关键词：代谢综合征；生活方式干预

英文关键词：Metabolicsyndrome；Lifestyleintervention

• 摘要：

• 目的探讨生活方式干预在中青年代谢综合征（MS）患者中的效果。方法以2017年1月至2018年12月在华中科技大学同济医学院附属武汉中心医院健康体检中心检出的886例中青年MS患者为研究对象，完全随机分为观察组和对照组，各443例。对照组行常规健康随访及定期检测，观察组进行常规健康随访、生活方式干预及定期检测。12个月后观察2组腰围、体重指数、血压、血脂和空腹血糖的变化。结果干预后，观察组体重指数、收缩压、总胆固醇、三酰甘油及空腹血糖水平均较干预前下降，且低于对照组［（25.0±2.8）kg/m2比（27.0±1.2）kg/m2、（135±15）mmHg（1 mmHg=0.133 kPa）比（145±18）mmHg、（5.3±1.5）mmol/L比（6.3±1.1）mmol/L、（2.2±0.6）mmol/L比（2.8±0.3）mmol/L、（6.0±1.0）mmol/L比（6.4±1.0）mmol/L］，而高密度脂蛋白胆固醇高于对照组［（1.6±0.4）mmol/L比（1.2±0.4）mmol/L］，差异均有统计学意义（均P<0.05）。干预后，观察组以上指标异常率均较干预前下降，且低于对照组，差异均有统计学意义（均P<0.05）。干预后观察组控制饮食、戒烟限酒、每天运动30 min以上、对血压血脂血糖正确认识、定时测血压、定期检测血脂血糖、认可健康管理的比例均高于对照组，差异均有统计学意义（均P<0.05）。结论生活方式干预可有效调节MS患者的血压、血脂和血糖水平。

• ObjectiveTo investigate the effect evaluation of lifestyle intervention in young and middle-aged patients with metabolic syndrome(MS). Methods From January 2017 to December 2018, 886 young and middle-aged MS patients detected in the medical examination center of Wuhan Central Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology were selected. They were randomly divided into observation group and control group, with 443 cases in each group. The control group was given regular health follow-up and regular testing, and the observation group was given regular health follow-up, lifestyle intervention, and regular testing. After 12 months, waistline, body mass index(BMI), blood pressure, blood lipid and fasting blood glucose(FBG) levels ，total cholesterol(TC), triacylglycerol, high density lipoprotein cholesterin(HDL-C), low density lipoprotein cholesterin(LDL-C)were observed.. Results    After intervention, the BMI, systolic blood pressure, TC, triacylglycerol and FBG in the observation group were lower than before intervention and those in the control group［（25.0±2.8）kg/m2 vs （27.0±1.2）kg/m2, （135±15）mmHg vs （145±18）mmHg, （5.3±1.5）mmol/L vs （6.3±1.1）mmol/L, （2.2±0.6）mmol/L vs （2.8±0.3）mmol/L, （6.0±1.0）mmol/L vs （6.4±1.0）mmol/L］, but HDL-C was higher than that of the control group［（1.6±0.4）mmol/L vs （1.2±0.4）mmol/L］, the differences were statistically significant(all P<0.05). After intervention, the abnormal rate of the above indexes in the observation group was lower than that before intervention, and the difference was statistically significant(all P<0.05). After intervention, the proportion of diet control, smoking cessation and alcohol restriction, exercise for more than 30 minutes per day, correct understanding of blood pressure, blood lipid and blood glucose, regular blood pressure measurement, regular blood lipid and blood glucose detection, and recognition of health management in the observation group were higher than those in the control group, the differences were statistically significant(all P<0.05). ConclusionLifestyle intervention can effectively regulate blood pressure, blood lipid and blood glucose levels in MS patients.