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2020 年第 8 期 第 15 卷

小儿肺热清颗粒治疗痰热壅肺型小儿急性支气管炎的临床观察

Treatment of acute bronchitis in children with phlegm-heat obstructing pulmonary type by Xiaoerfeireqing granule

作者:刘应科杨晔王秋莉张辰白万红范菲

英文作者:Liu Yingke Yang Ye Wang Qiuli Zhang Chen Bai Wanhong Fan Fe le

单位:北京市和平里医院儿科100013

英文单位:Department of Pediatrics Beijing Hepingli Hospital Beijing 100013 China

关键词:小儿急性支气管炎;小儿肺热清颗粒;痰热壅肺

英文关键词:Acutebronchitisinchildren;Xiaoerfeireqinggranule;Phlegm-heatobstructinglung 

  • 摘要:
  • 目的 观察小儿肺热清颗粒治疗痰热壅肺型小儿急性支气管炎的效果及安全性。方法 选择2019512月就诊于北京市和平里医院儿科门诊的212岁痰热壅肺型小儿急性支气管炎患儿120例,按照随机数字表法分成对照组和观察组,各60例,分别在基线治疗的基础上联合氨溴特罗口服溶液和小儿肺热清颗粒治疗,疗程5 d。观察2组西医症状疗效、中医证候积分疗效、咳嗽症状积分和安全性情况。结果 治疗过程中,对照组5例脱落,脱落率为8.3%,观察组3例脱落,脱落率为5.0%2组脱落率差异无统计学意义(P0.05)。观察组西医症状疗效总有效率与对照组比较[89.5%(51/57)92.7%(51/55)],差异无统计学意义(P0.05)。观察组中医症候积分总有效率明显高于对照组[91.2%(52/57)78.2%(43/55)],差异有统计学意义(P0.05)。治疗后,2组咳嗽症状积分均明显低于治疗前[观察组:(1.0±0.6)分比(3.5±1.0)分;对照组:(1.0±0.6)分比(3.7±1.0)分],差异均有统计学意义(均P0.05),但2组间比较差异无统计学意义(P0.05)。2组不良反应发生率比较差异无统计学意义(P0.05)。结论 小儿肺热清颗粒治疗痰热壅肺型小儿急性支气管炎疗效确切,并有良好的依从性和安全性。

  • Objective To observe the efficacy and safety of Xiaoerfeireqing granule treating acute bronchitis in children with phlegm-heat obstructing lung type. Methods A total of 120 children aged 2-12 years old with acute bronchitis of phlegm-heat obstructing lung type were randomly divided into control group (60 cases) and observation group (60 cases).The control group had ambroterol oral solution on the basis of baseline treatment; the observation group had pediatric lunreqing granules on the basis of baseline treatment. The course of treatment in both groups was 5 days. The clinical curative effect, traditional Chinese medicine (TCM) syndrome integral curative effect, cough symptom integral effect and safety of 2 groups were observed. Results During the treatment, 5 children (8.3%) in the control group and 3 children (5.0%) in the observation group were dropped. There was no statistically significant difference in the dropped rate between the two groups (P0.05). The total effective rate of the observation group and the control group was 89.5% (51/57) vs 92.7% (51/55); there was no significant difference (P0.05). The total effective rate of TCM symptom scores in the observation group was significantly higher than that in the control group 91.2% (52/57) vs 78.2% (43/55), P0.05. After treatment, the scores of cough symptoms in the two groups were significantly lower than those before treatmentobservation group:(1.0±0.6 vs 3.5±1.0); control group:(1.0±0.6 vs 3.7±1.0)] (P0.05), but there was no significant difference between the two groups (P0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P0.05). Conclusion Xiaoerfeireqing granule has definite curative effects, with good compliance and safety in treating children acute bronchitis of phlegm-heat obstructing lung type.

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