2020 年第 8 期 第 15 卷

射频消融术对心房颤动患者术后1年认知功能的影响

Effect of radiofrequency ablation on cognitive function of patients with atrial fibrillation at 1 year after operation

作者：闫晓涵黄曼芸王鑫陆吴永全

英文作者：Yan Xiaohan Huang Manyun Wang Xinlu Wu Yongquan 

单位：首都医科大学附属北京安贞医院心内科100029

英文单位：Department of Cardiology Beijing Anzhen Hospital Capital Medical University Beijing 100029 China

关键词：心房颤动；射频消融；认知功能

英文关键词：Atrialfibrillation；Radiofrequencyablation；Cognitivefunction

• 摘要：

• 目的 探讨射频消融术（RFCA）对心房颤动患者术后1年认知功能的影响。方法 采用前瞻性观察研究设计，入选2018年6月21日至2019年1月30日在首都医科大学附属北京安贞医院住院并首次行RFCA的非瓣膜性心房颤动患者128例作为观察组，纳入同期在医院门诊仅接受药物治疗的心房颤动患者41例作为对照组。在入组时及入组后12个月分别使用认知功能电话问卷修订版（TICS-m）评估2组患者的认知功能并进行比较。结果 观察组患者入组时的TICS-m评分与对照组比较［37（35,39）分比37（34,38）分］，差异无统计学意义（P=0.320），入组后12个月，观察组患者TICS-m评分显著高于对照组［39(36,40)分比35（32，37）分］，差异有统计学意义（P＜0.001）。结论 RFCA联合药物治疗心房颤动患者术后1年的认知功能优于单用药物治疗患者。

• Objective To investigate the effect of radiofrequency ablation（RFCA） on cognitive function of patients with atrial fibrillation at 1 year after operation. Methods A total of 128 patients with non-valvular atrial fibrillation and RFCA admitted to Beijing Anzhen Hospital， Capital Medical University， from June 21, 2018 to January 30, 2019 were selected as observation group. During the same period, 41 patients with atrial fibrillation who only received drug treatment were served as control group. The control group was only treated with drugs, while observation group was treated by RFCA and drugs. The cognitive function telephone questionnaire revision (TICS-m) was used to evaluate the cognitive function, and the cognitive function was compared between the two group at the time of enrollment and 12 months after enrollment.Results There were no significant difference in cognitive function between observation group and control group ［37(35,39) vs37(34,38)，P=0.320］. After 12 months, TICS-m score in observation group was significantly higher than that in control group［39(36,40) vs 35(32,37), P＜0.001］. Conclusion The improvement of cognitive function in atrial fibrillation patients treated by RFCA combined with medication is more significant than that by medication alone.