2020 年第 1 期 第 15 卷

经皮冠状动脉介入术后患者并发焦虑抑郁的研究进展

Review on postoperative anxiety and depression after percutaneous coronary intervention

作者：王思璇1杨宇彤1高阳1马涵英2

英文作者：

单位：1首都医科大学第六临床医学院2015级临床医学专业,北京100069；2首都医科大学附属北京安贞医院全科医疗科100029

英文单位：

关键词：经皮冠状动脉介入；焦虑；抑郁

英文关键词：

• 摘要：

• 【摘要】冠状动脉粥样硬化性心脏病（冠心病）经皮冠状动脉介入（PCI）术后患者出现焦虑抑郁的比例较高。焦虑抑郁状态是冠心病PCI术后患者再发主要心血管不良事件的独立预测因子，且抑郁情绪使冠心病PCI术后患者死亡率明显增高。PCI术后患者发生焦虑抑郁的机制主要与大脑“边缘系统-纹状体-丘脑”神经递质环路被阻断有关，其危险因素主要是性别、年龄、受教育程度、家庭经济条件等基本因素和冠状动脉病变严重程度以及D型人格，治疗上为心理干预、护理干预和中西医药物治疗。

• 【Abstract】There is a high incidence of anxiety and depression among patients after percutaneous coronary intervention(PCI). Anxiety and depression are independent predictors of major adverse cardiovascular events and death following PCI. The pathogenesis of anxiety and depression in post-PCI patients is mainly associated with the interception of neurotransmitters in brain′s limbic system-striatum-thalamic loop. Risk factors of post-PCI anxiety and depression are gender, age, education, financial status, as well as the severity of coronary lesion and type D personality, etc. Major treatments include psychological intervention, nursing care, traditional Chinese medicine and western medicine.