2019 年第 9 期 第 14 卷

性别对心房颤动导管射频消融并发心脏压塞的影响

Influence of gender on cardiac tamponade following atrial fibrillation ablation

作者：阮燕菲李林凌赵倩倩张梦夏刘念杜昕董建增马长生

英文作者：

单位：100029首都医科大学附属北京安贞医院心内科北京市心肺血管疾病研究所

英文单位：

关键词：心房颤动；导管射频消融；性别；心脏压塞

英文关键词：

• 摘要：

• 【摘要】目的    研究性别与心房颤动导管射频消融并发心脏压塞的相关性。方法    回顾性收集2013年1月至2016年12月于首都医科大学附属北京安贞医院行首次心房颤动导管射频消融术5 313例患者的临床资料，分为男性组（3 524例）和女性组（1 789例）。探讨性别与心脏压塞发生风险的相关性。结果    发生心脏压塞41例（0.8%）。男性组和女性组心脏压塞发生率比较，差异无统计学意义［0.8%(27/3 524)比0.8%(14/1 789)］（P＝0.949）。2组心包引流量差异无统计学意义［（436±349）ml比（309±133）ml］(P＝0.198）。每组各有4例并发延迟心脏压塞，其中男性组中1例行急诊外科开胸心脏修补术。无院内死亡患者。对年龄（60岁）、口服抗凝药物、左心房内径（40 mm）、左心室射血分数（64%）和手术时间（120 min）进行分层分析，结果显示男性组和女性组心脏压塞发生率差异无统计学意义（P＞0.05）。结论    女性并不增加心房颤动导管射频消融术心脏压塞发生的风险。

• 【Abstract】Objective    To analyze the relation between gender and cardiac tamponade following atrial fibrillation ablation. Methods    From January 2013 to December 2016, 5 313 patients undergoing initial atrial fibrillation radiofrequency catheter ablation in Beijing Anzhen Hospital, Capital Medical University were retrospectively analyzed. The patients were divided into male group（3 524 cases） and female group（1 789 cases）. Relation between gender and the occurrence of cardiac tamponade was analyzed. Results    Cardiac tamponade occurred in 41 patients（0.8%）. The incidence of cardiac tamponade was identical between male group and female group［0.8%(27/3 524) vs 0.8%(14/1 789)］（P＝0.949）. The volume of pericardial drainage was comparable between the two groups［（436±349）ml vs （309±133）ml］(P＝0.198）. Four cases of delayed cardiac tamponade occurred in each group; 1 patient in male group had emergency cardiac repair through surgical thoracotomy. No patients died in hospital. Subgroup analysis stratified by age(60 years old), oral anticoagulants, left atrium dimension（40 mm）, left ventricular ejection fraction(64%) and procedure duration（120 min） revealed that female did not increase the incidence of cardiac tamponade（P＞0.05）. Conclusion    Female dose not increase the risk of cardiac tamponade following atrial fibrillation ablation.