2019 年第 8 期 第 14 卷

棘突球囊在冠状动脉中重度钙化病变患者介入治疗中的应用效果及安全性分析

Effect and safety of Lacrosse non-slip element balloon in coronary intervention for patients with moderate to severe calcified lesions

作者：张新勇艾辉阙斌王春梅李庆祥王梅赵雪东聂绍平

英文作者：

单位：100029首都医科大学附属北京安贞医院急诊危重症中心北京市心肺血管疾病研究所

英文单位：

关键词：冠状动脉钙化；经皮冠状动脉介入；棘突球囊

英文关键词：

• 摘要：

• 【摘要】目的    探讨棘突球囊在冠状动脉中重度钙化病变患者经皮冠状动脉介入（PCI）治疗中的应用效果及安全性。方法    选择首都医科大学附属北京安贞医院2016年1—6月行PCI治疗的冠状动脉中重度钙化患者60例，均应用棘突球囊对病变进行扩张并置入药物洗脱支架。观察患者PCI术后即刻支架置入情况和血管内超声检查结果、围术期并发症发生率及术后6个月主要心血管不良事件发生率。结果    共治疗67支血管,72个中重度钙化病变，置入支架72枚，手术均成功。棘突球囊扩张后即刻血管获得率为（146±13）%，支架膨胀率为（93±6）%，支架对称性良好者占90.3%(65/72)，血管夹层发生率为9.7%（7/72），无冠状动脉穿孔发生。术后6个月内有2例（3.3%）患者发生心绞痛，无心肌梗死及死亡。术后6个月冠状动脉造影支架内再狭窄3例（5.0%），其中1例行冠状动脉血运重建。结论    棘突球囊用于冠状动脉中重度钙化病变患者PCI治疗，可有效扩张狭窄血管，实现理想的支架置入，且安全性高。

• 【Abstract】Objective    To explore the effectiveness and safety of Lacrosse non-slip element (NSE) balloon in percutaneous coronary intervention(PCI) for patients with moderate to severe coronary artery calcification. Methods    Sixty patients with moderate to severe calcified coronary lesions who underwent PCI in Beijing Anzhen Hospital, Capital Medical University from January to June 2016 were enrolled. All patients had balloon angioplasty using Lacrosse NSE and drug-eluting stent implantation. Operation and stent records, intravascular ultrasound results, perioperative complications and major cardiovascular adverse events in 6 months after PCI were observed. Results    Among the 60 patients, 67 vessels and 72 locations of calcification were treated; 72 stents were successfully implanted during PCI. After Lacrosse NSE balloon angioplasty, the immediate lumen access rate, stent expansion rate, percentage of satisfactory stent symmetry and incidence of vascular dissection were （146±13）%, （93±6）%, 90.3%（65/72） and 9.7%（7/72）, respectively; no coronary artery perforation occurred. During 6-month follow-up, there were 2 patients（3.3%） having angina pectoris, 3 patients（5.0%） having stent re-stenosis and 1 patient undergoing revascularization; no myocardial infarction or death was reported. Conclusion    PCI with Lacrosse NSE balloon treating moderate to severe coronary artery calcification can effectively dilate stenosis and achieve ideal stent placement with good safety.