2018 年第 6 期 第 13 卷

心脏康复用于急性冠状动脉综合征的疗效及对患者生活质量的影响

Effect of cardiac rehabilitation on acute coronary syndrome and quality of life

作者：康铁朵刘文娴康云鹏任燕龙

英文作者：

单位：100029首都医科大学附属北京安贞医院心内科北京市心肺血管疾病研究所

英文单位：

关键词：急性冠状动脉综合征；心脏康复；心肺功能；生活质量

英文关键词：

• 摘要：

• 【摘要】目的    观察心脏康复用于急性冠状动脉综合征（ACS）的疗效及对患者生活质量的影响。方法    选取2016年1月至2017年2月首都医科大学附属北京安贞医院收治的93例ACS患者，按随机数字表法分为对照组（46例）和观察组（47例）。对照组给予规范化冠状动脉粥样硬化性心脏病二级预防治疗；观察组在对照组的基础上加用心脏康复治疗，6个月为1个疗程。比较2组疗效、心功能、6 min步行距离（6MWD）、心肺运动试验（CPET）指标、SF-36健康状况调查量表生活质量评分。结果    观察组总有效率明显高于对照组［68.1%（32/47）比41.3%（19/46）］，差异有统计学意义（P＜0.05）。治疗后，对照组心功能和6MWD无明显改善，观察组左心室射血分数、6MWD明显高于/长于治疗前和对照组［（48±4）%比（42±5）%、（42±6）%，（359±50）m比（280±35）、（303±33）m］，差异均有统计学意义（均P＜0.05）。治疗后，2组CPET各指标均有不同程度改善，观察组用力肺活量、无氧阈摄氧量、峰值功率及峰值氧脉搏明显高于对照组，差异均有统计学意义（均P＜0.05）。治疗后，2组SF-36量表评分均有不同程度改善，组间比较，观察组生理机能、一般健康、精力、精神健康及总分明显高于对照组，差异均有统计学意义（均P＜0.05）。结论    心脏康复能明显改善ACS患者心肺功能、运动能力和生活质量。 

• 【Abstract】Objective    To observe the effect of cardiac rehabilitation on acute coronary syndrome(ACS) and quality of life. Methods    A total of 93 ACS patients admitted in Beijing Anzhen Hospital, Capital Medical University from January 2016 to February 2017 were randomly divided into control group(n＝46) and observation group(n＝47). The control group had secondary preventive therapy of coronary heart disease; the observation group had cardiac rehabilitation additionally, with 6 months for a course of treatment. Therapeutic effect, heart function, 6 min walking distance (6MWD), results of cardiopulmonary exercise test and the SF-36 score were analyzed. Results    Total effective rate in observation group was significantly higher than that in control group［68.1%（32/47） vs 41.3%（19/46）］（P＜0.05）. After treatment, heart function and 6MWD in control group showed no significant improvements; left ventricular ejection fraction and 6MWD in observation group were significantly higher/longer than those before treatment and those in control group［（48±4）% vs（42±5）%,（42±6）%; （359±50）m vs（280±35）,（303±33）m］(P＜0.05). After treatment, forced vital capacity, anaerobic threshold oxygen consumption, peak respiratory power and peak oxygen pulse in observation group were significantly higher than those in control group（P＜0.05）. After treatment, scores of physiological function, general health, vigor, mental health and the total SF-36 score in observation group were significantly higher than those in control group(P＜0.05). Conclusion    Cardiac rehabilitation can effectively improve cardiopulmonary function, athletic performance and quality of life in ACS patients.